Water pills just as effective as pricey blood-pressure drugs: study
Generic blood pressure drugs are just as good as newer, more expensive ones, according to new data out of the study known as the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
When researchers followed up with ALLHAT participants taking one of three classes of blood pressure drugs for an average of 8.8 years, they found that a generic diuretic (chlorthalidone) was just as effective at lowering blood pressure and preventing heart attack and stroke as a name-brand calcium channel blocker (Norvascor) or ACE inhibitor (Prinivil, Zestril).
Researchers from Loyola University Health System recently confirmed that, in the long term, older diuretics are the same, if not better, at preventing cardiovascular disease.
Diuretics are sometimes called water pills. They help kidneys to remove sodium and water from the body, relaxing the blood vessel walls. Participants were randomly assigned to take a diuretic, the calcium channel blocker, amlodipine, or the ACE inhibitor, lisinopril.
People taking the diuretic had a lower stroke risk than those taking the ACE inhibitor; and a lower risk of hospitalization or dying from heart failure than those taking the calcium channel blocker. Diuretics are generally cheaper than newer drugs which can cost several hundred dollars a year. But diuretics account for only about 30 percent of hypertension prescriptions written today.
|